Clinical & Translational Research
The mission of the Clinical and Translation Research Program (CTR) is to accelerate the delivery of new therapies and treatment innovations to the patients at Children’s Memorial.
We are dedicated to creating a vibrant and enterprise-wide research environment that fosters and expedites translational research while adhering to the highest scientific and ethical standards involving our vulnerable human subjects.
Under the leadership of Ram Yogev, MD, and with 135 members representing all departments and divisions of Children’s Memorial, CTR provides a home to investigators engaged in both clinical trials and bench-to-bedside research. To achieve our mission, during the past year we have continued developing the research culture.
Researchers thrive with targeted education. CTR is developing education and training programs directed at researchers as well as the clinical research associates supporting them.
The Biostatistics Research Core (BRC) strengthens projects. Research projects, grant proposals, IRB proposals, scientific presentations and publications all benefit from the scrutiny of biostatisticians who assist with study design, sample size calculations and data analysis.
Four centers of excellence are established. These centers embody the clinical and translational goals for developing novel treatments and therapies for our pediatric population:
Retinoblastoma Center of Excellence: a collaborative effort working toward a cure for retinoblastoma, a rare pediatric cancer of the retina.
Pediatric Drug Development Center: a multidisciplinary enterprise focused on re-developing and re-purposing drugs for pediatric rare diseases. Its members perform translational research and educate physicians and scientists.
Center for Gender, Sexuality and HIV Prevention: a new venture committed to caring for high-risk adolescent populations through clinical care, education and evaluation as well as professional training, research and advocacy. The center strives to collaborate with like-minded organizations on projects of public health significance.
Center for Intestinal and Liver Inflammation Research: a base for integrating efforts on inflammation research with broad links across disciplines and disease processes. The center fosters interdisciplinary cooperation and provides mentorship to trainees in basic research and clinical applications.
In its strategic planning meeting, the research center board of directors underscored the importance of the CTR program by setting as a high priority the recruitment of a full-time director for the program, fostering its continued development.